![Update on RYR1-related myopathies Update on RYR1-related myopathies](https://ryr1.org/wp-content/uploads/2024/08/Screenshot-2024-08-20-at-12.29.26 PM.jpg)
Update on RYR1-related myopathies
Masashi Ogasawaraa and Ichizo Nishino
Purpose of Review
RYR1-related myopathy (RYR1-RM) is a group of myopathies caused by mutations in the RYR1 gene, which encodes the ryanodine receptor 1 (RYR1). This review discusses recent advances in the clinical features, pathology, pathogenesis, and therapeutics of RYR1-RM.