James Dowling, MD, PhD
Dr. Dowling is a clinician-scientist who is focused on gene discovery and therapy for childhood muscle diseases. He is a Professor of Paediatrics and Molecular Genetics at the University of Toronto and a staff clinician at the Hospital for Sick Children in Toronto. He is also the inaugural Mogford Campbell Chair in Pediatric Clinical Neuroscience at Toronto’s Hospital for Sick Children. In addition, he is a member of the Executive Board of the World Muscle Society and Chair of the Executive Committee of TREAT-NMD.
Dr. Dowling is considered one of the world’s leading experts in RYR-1-related diseases. His research spans the continuum from new gene discovery to disease pathogenesis to therapy development. He is engaged in both targeted and non-biased drug discovery for RYR-1-related diseases. His laboratory employs both the zebrafish and mouse model systems, along with complementary in vitro analyses. Dr. Dowling is the recipient of numerous NIH and private foundation research grants and has recently published detailed results of his RYR-1-related research.
